@harshil Hello, the three over-the-counter are acetaminophen, aspirin, and ibuprofen, ibuprofen has the best anti-inflammatory properties. Ibuprofen is sold as generic or brand name Motrin or Advil. It not only decreases pain but is superior to aspirin and Tylenol in decreasing swelling as well. Therefore, for muscle injuries, ibuprofen would be the better choice provided you don’t have any contraindications such as allergies to the drug, gastric ulcers, heart disease, etc. Please discuss this with your doctor before taking medicine. thanks!!!