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    Prognosis of Drug-Induced Lupus Erythematosus ??

    Dermatology & Cosmetic Care
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      Ayra last edited by

      Drug-induced lupus erythematosus (DILE) is a variant of lupus erythematosus that resolves within days to months after withdrawal of the culprit drug in a patient with no underlying immune system dysfunction. DILE can arise months to years after exposure to drugs prescribed to treat various medical conditions (eg, antihypertensives, antibiotics, anticonvulsants). The most common drugs that cause DILE are hydralazine, procainamide, quinidine, isoniazid, diltiazem, targeted immunotherapy, and minocycline. What is the prognosis of this disease?

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        Rohini @Ayra last edited by

        @ayra Prognosis is excellent once the causative medication is discontinued. Recovery generally occurs within days or weeks. Death from DILE is extremely rare and may result from renal involvement (see Complications). In diagnosing this condition, it is extremely crucial to first exclude the possibility that the patient has renal idiopathic lupus rather than DILE with renal involvement.

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