Use of tighter glycemic targets for women with gestational diabetes mellitus (GDM) reduced the risk for a serious health outcome for the infant, according to a trial conducted in New Zealand. These serious health outcomes included death, birth trauma, and shoulder dystocia. Infants' length of stay in the neonatal intensive care unit also was shorter. But the new targets did not reduce the infant's risk of being large for its gestational age. For the women, there was an increase in the risk for serious health outcomes, including postpartum hemorrhage, and an increased use of pharmacologic therapy to treat their hyperglycemia. These findings were reported in a recent article in PLOS Medicine.

Previous research has shown the beneficial effects of exercise on motor and cognitive function, as well as nonmotor symptoms such as mood and sleep in PD. However, these studies were small with relatively short follow-up and few examined the association between physical activity and mortality in this patient population. In the new study, researchers used data from the National Health Insurance Service, a single-payer system providing universal medical coverage for most citizens of South Korea.

You know physical activity helps kids build strong muscles and bones, and lowers the risk of things like heart disease and diabetes later in life. Now researchers from Australia reveal another reason to encourage your child to move: It may help them stay mentally sharp for decades. A new study followed 1,200 people for 30 years and revealed a link between childhood fitness and cognitive performance in middle age.

The long-term neurologic symptoms such as "brain fog" experienced by some patients with COVID-19 may be caused by a unique pathology — the occlusion of brain capillaries by large megakaryocyte cells, a new report suggests. The authors report five separate post-mortem cases from patients who died with COVID-19 in which large cells resembling megakaryocytes were identified in cortical capillaries. Immunohistochemistry subsequently confirmed their megakaryocyte identity. They point out that the finding is of interest as — to their knowledge — megakaryocytes have not been found in the brain before.

The high cost of a sedentary lifestyle just became a bit more evident ― a new global study shows that inactivity drives up to 8% of noncommunicable diseases and mortality. Physical inactivity, defined as engaging in less than 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity physical activity per week, is estimated to have caused 7.2% (95% CI, 5.4 – 9.0) of all-cause deaths and 7.6% (95% CI, 6.1 – 9.3) of cardiovascular disease (CVD) deaths, according to investigators led by Peter T. Katzmarzyk, PhD, associate executive director for population and public health sciences, Pennington Biomedical Research Center, Baton Rouge, Louisiana.

@mandeep The majority of friction blisters heal on their own within 1–2 weeks. However, a few simple steps can help reduce discomfort and minimize the likelihood of the blister becoming infected.
The American Academy of Dermatology Association (AAD) notes that people can treat a friction blister in the following ways:
Protect and cover the blister
People can use a padded bandage, dressing, or soft Band-Aid to protect the affected area. If the blister is in an area subject to pressure, such as the bottom of the foot, padding might be a better option to help prevent further friction from aggravating the blister.
Hydrocolloid blister plasters can also help the blister heal faster by creating the moist conditions that the skin needs to repair itself. People can purchase these plasters at most drugstores. If possible, people should try to resist the temptation to pop a blister at home. Popping the blister can open the wound to infection and may slow the healing process.
However, if a friction blister is uncomfortable or likely to burst by itself, it may be preferable to drain the fluid in a sterile and controlled way. People can do this by:
washing the hands thoroughly with soap and water
sterilizing a small needle using rubbing alcohol or heat
inserting the needle carefully and gently into the edge of the blister and allowing the fluid to drain out

@abhik Headaches, the sharp, throbbing, uncomfortable pains that occur in multiple regions of your head, are common occurrences. In fact, up to 80 percent of adults experience tension headaches. However, when headaches are linked with depression, you could be dealing with other chronic issues, too. Treating depression headaches can involve a multipronged approach, depending on the underlying causes. You may need treatment for both the headache and depression symptoms. Talk to your doctor about the following options. Certain prescription medications may be used to treat both depression and anxiety as well as migraine. These include tricyclic antidepressants, monoamine oxidase inhibitors, and anxiolytics. Selective serotonin reuptake inhibitors (SSRIs) are the most common medications used to treat depression. Examples include Zoloft, Paxil, and Prozac.

@anushtup Augmented and virtual reality (AR and VR) have several applications in the medical world. Simulated and hybrid environments have found a natural fit in medical education, providing simulation training that enhances and works alongside traditional school. Immersive learning with AR and VR headsets can cater to several different learning styles at once by engaging the full range of senses: audio, visual, and kinesthetic. VR can be used in physical therapy to help patients recover from complex limb injuries and even has applications in areas like mental trauma where it can alleviate phobias and PTSD through customized exposure and treatment. In the surgical theater, Cambridge Consultants developed AR glasses that let surgeons see the inside of a patient’s body by superimposing data from 3D scans and CAT scans. This provides a revolutionary level of visibility into minimally invasive “keyhole surgeries,” and requires practically no additional training to use. Based on the low learning curve and relatively low cost of use, further developments should see the medical landscape further merge with augmented and virtual reality.

Hello, my mother is 52 years old. She is suffering from angular stomatitis. Her symptoms include bleeding, blistered, cracked, crusty, itchy and painful corner inside her mouth. Please help me with your suggestion.

Hello, my 30 year old boyfriend presented with complaints of pain in his arch and also on the outside of the right ankle dur to flat foot. The pain was worse when walking long distances and when jogging. He had previously been provided with orthotics but these did not resolve the problem. He is suffering a lot. I feel bad for him and at a loss what to do. Please suggest.