@sasical In a feasibility study of more than 2000 patients seen at diabetes clinics, clinicians entered patient data into the app, which takes about 20 seconds. Based on the data, the app classified CV risk in the cohort as very high (72.2% of patients), high (9.9%), or moderate (0.8%). However, 18.2% of patients did not fit any of the risk categories and were deemed to have moderate to high CV risk.

@milind-m COVID-19 patients with cognitive issues received 40 sessions of therapy in a special hyperbaric chamber over a period of 60 days. In each session, they spent 90 minutes breathing through a mask. One group received pure oxygen; the control group received normal air, which has less oxygen.

@mansoor A MyProstateScore of 15 or below had a 100% negative predictive value and sensitivity for GG ≥ 2 cancer and would have prevented 23% of unnecessary biopsies. A score above 40 had a 19% risk of GG ≥ 2 disease. A score of 15 to 40 had a 6.5% risk of GG ≥ 2 disease. Together, the data suggest that men with a MyProstateScore of 15 or below can "confidently forego biopsy," that most men with scores of 15-40 "are unlikely to benefit from repeat biopsy," and a score greater than 40 "supports proceeding to repeat biopsy."

@vatan Periodontal diseases are mainly the result of infections and inflammation of the gums and bone that surround and support the teeth. In its early stage, called gingivitis, the gums can become swollen and red and may bleed. In its more serious form, periodontitis, the gums can pull away from the tooth, bone can be lost, and the teeth may loosen or even fall out. Periodontal disease is mostly seen in adults. According to the US Centers for Disease Control and Prevention, periodontal disease and tooth decay are the two biggest threats to dental health. Periodontitis is more common in men than women (56.4% vs 38.4%), those living below the federal poverty level (65.4%), those with less than a high school education (66.9%), and current smokers (64.2%). Although periodontitis is more common in adults and the elderly, the disease can also occur in children and adolescents. Early diagnosis and treatment are essential to managing the disease. To best manage periodontitis and systemic diseases, patients should see their doctors on a regular basis.

@pinaki The FDA has tentatively scheduled meetings of its Vaccines and Related Biological Products Advisory Committee in June to consider the applications, saying that it "understands the urgency to authorize a vaccine for age groups who are not currently eligible for vaccination and will work diligently to complete our evaluation of the data. Should any of the submissions be completed in a timely manner and the data support a clear path forward following our evaluation, the FDA will act quickly" to convene the necessary meetings. The need for greater access to vaccines seems to be increasing, as new pediatric COVID cases rose for the third consecutive week. April 22-28 saw over 53,000 new cases reported in children, up 43.5% from the previous week and up 105% since cases started rising again after dipping under 26,000 during the week of April 1-7, based on data from the American Academy of Pediatrics and the Children's Hospital Association.

Hospital admission for children with eating disorders approximately tripled during the COVID-19 pandemic, based on data from 85 patients. Eating disorders are common among adolescents and often require hospital admission for nutritional restoration, according to May Shum of Yale University, New Haven, Conn., and colleagues. During the COVID-19 pandemic, the volume of hospital admissions for adolescents with eating disorders has increased, the researchers wrote in a poster presented at the annual meeting of the Pediatric Academic Societies. This increase may be driven both by interruptions in medical care and increased psychological distress, but data on changes in patient characteristics and hospitalization course are lacking, they said.

@vatan A significantly higher proportion of cold-induced urticaria patients had comorbid asthma and atopic dermatitis compared to chronic spontaneous urticaria patients. The researchers collected data on severity, comorbidities, laboratory values, management, and demographics at baseline and in annual evaluations. To compare children with coldU to those with only CSU, they extracted data from children in a previous study that had used the same registry. Slightly more than half the children with coldU recruited for the study were girls, and the median age at symptom onset among all participants was 9.5 years. Their coldU triggers included swimming, cold weather or air, and cold food or drink. Most patients were taking second-generation H1-antihistamines (sgAHs) to treat the condition.

@bodhi Weight loss with intermittent fasting appears to be similar to that attained with caloric restriction, but in the case of those with diabetes, the best way to adjust glucose-lowering medicines to reduce the risk of hypoglycemia while practicing intermittent fasting has not been established, and there is potential for such fasting to cause glycemic variability. Things such as low blood pressure, weakness, headaches and dizziness are considerations, but the big issue is hypoglycemia, so caloric restriction may be a better choice for some patients with diabetes.

"Responsible drinking" has become a 21st-century mantra for how most people view alcohol consumption. But when it comes to cancer, no amount of alcohol is safe. That is the conclusion of the 2014 World Cancer Report (WCR), issued by the World Health Organization's International Agency for Research on Cancer (IARC). Declared a carcinogen by the IARC in 1988, alcohol is causally related to several cancers.

Whether it’s the latest gadget, a chic new piece of clothing, or even food, we’ve all felt the urge to splurge now and again. This comes as little surprise because we are constantly bombarded with online, print, and media ads that reinforce shopping mentality. Indulging in occasional spending isn’t necessarily a bad thing when it done in moderation and doesn’t disrupt family finances. If your urge to shop becomes uncontrollable and if you are constantly spending beyond your means on things that you don’t need, a shopping addiction can be just as damaging as gambling or alcoholism. Please provide some corrective measures.