@sarkarsatarupa Patients should be closely monitored for the emergence of major depression or bipolar disorder. Review of longitudinal studies showed that 76% of dysthymic children developed major depression and that 13% developed bipolar disorder over follow-up periods of 3–12 years.
Patients with dysthymia have a higher risk of employment problems, including decreased productivity and increased unemployment. A study found that at 6 months, 14% of patients with dysthymia were newly unemployed, compared with 2% new unemployment in the control group and 3% new unemployment in a group with rheumatoid arthritis.
Additional concerns in dysthymia include the following:
Increased mortality and morbidity from unrelated physical illnesses - dysthymia is associated with poorer self-rated health status
Suicide, attempted or completed - dysthymia significantly increases risk of suicide