@jack-jason Women who received usual care following cesarean section were more likely to have uterine contractions at the umbilical level compared with the skin-to-skin contact group (70% vs. 3%; P ≤ .0001), while the skin-to-skin group was more likely to have uterine contractions at the infraumbilical level (92.5% vs. 22.5%; P ≤ .0001). There was a statistically significant decrease in predischarge hemoglobin in the control group compared with the skin-to-skin group (10.522 vs. 11.075 g/dL; P ≤ .017); the level of hemoglobin reduction favored the skin-to-skin group (1.01 vs. 2.265 g/dL; P ≤ .0001). Women in the skin-to-skin group were more likely to report mild pain on a 10-point visual analog scale (VAS) after being transferred to the recovery room (1.48 vs. 6.23 points; P ≤ .0001) and being transferred to a maternity room or room in the postpartum unit (0.60 vs. 5.23 points; P ≤ .0001). Breastfeeding at birth was significantly higher among patients with immediate skin-to-skin contact compared with the control group (92.5% vs. 32.5%; P ≤ .0001), and continued at 1 month after birth (92.5% vs. 12.5%; P ≤ .0001). Newborns of mothers in the skin-to-skin group were significantly less likely to cry compared with newborns in the control group (90% vs. 55%; P ≤ .001).

Two biomarkers linked to endothelial activation, measured in young adulthood, may predict subclinical myocardial changes in middle age that herald later heart failure with preserved ejection fraction (HFpEF), say researchers who conducted an observational study. Elevations in the two inflammatory biomarkers — cellular adhesion molecules E-selectin and ICAM-1 — are considered signs of endothelial activation and markers of existing HFpEF.

@kevin Despite the recent surge in the popularity of intermittent fasting, "only a few studies have examined the health benefits of these diets in humans.
They identified 21 clinical trials of three types of intermittent fasting strategies:
Alternate day fasting (alternating between consuming 0 to 500 kcal on "fasting" days, followed by unlimited food on "feasting" days), six trials.
5:2 diet ("feasting" on 5 days and "fasting" on 2 days), seven trials.
Time-restricted eating (eating during a 4- to 8- hour window), nine trials.

Women with polycystic ovary syndrome (PCOS) face an almost 30% increased risk for COVID-19 compared with unaffected women, even after adjusting for cardiometabolic and other related factors, suggests an analysis of United Kingdom primary care data. Before the onset of the COVID-19 pandemic, women with PCOS consistently report fragmented care, delayed diagnosis and a perception of poor clinician understanding of their condition

@kevin The main outcome measures were bulbar conjunctival hyperemia, ocular surface temperature, and ocular symptoms; these were measured at baseline and every 10 minutes after treatment for 1 hour. Symptoms were reduced more by all treatments than no treatment (P < .001), but all nonpharmaceutical treatments failed to return global ocular symptom scores to baseline levels within 1 hour after antigen exposure (no treatment, 58.6% relative return to baseline; CC, 71.6%; ATs, 84.8%; and ATs plus CC, 86.9%; P < .001). Hyperemia was reduced more by ATs combined with CC than other treatments (P < .05). No treatment reduced hyperemia to baseline levels within 60 minutes (no treatment, 16.5% relative return to baseline; CC, 57.9%; ATs, 73.3%; and ATs plus CC, 76.5%; P < .001), but they all improved hyperemia both nasally and temporally significantly more compared with no treatment (P < .05).

@abhik The succession of erection, emission, ejaculation, and orgasm creates the impression that these events might have a common physiologic substrate. In reality, they are separate events. This separateness is clearly illustrated by the typical patient with MOD, who complains of sustaining hard erections without being able to ejaculate, or by the typical patient with erectile dysfunction, who complains of ejaculating through a flaccid penis.
When pharmacotherapy for delayed ejaculation is under consideration, it is important to eliminate iatrogenic causes, including medications (eg, alpha-adrenergic blockers, other antihypertensives, antidepressants, and antipsychotics). In the case of antidepressant-induced inhibited male orgasm, consideration may be given to switching to bupropion (also used as adjunctive therapy), mirtazapine, nefazodone, or vilazodone, which have fewer sexual side effects than selective serotonin reuptake inhibitors (SSRIs) do.

Hello, I would like to understand what is Nanomedicine and how will it work? I learnt that the nanomedicine industry offers enormous potential and welcomes early investors. Please elaborate on this.

Hello, I am exploring Ayurvedic therapies for treating COVID 19. I have aversion in allopathy. So, I believe Ayurvedic option can be a good alternative. Please leave your comments on it.

@farhid Smoking tobacco is both a physical addiction and a psychological habit. The nicotine from cigarettes provides a temporary high addiction. Eliminating that regular fix of nicotine causes your body to experience physical withdrawal symptoms and cravings. Because of nicotine’s “feel good” effect on the brain, you may turn to cigarettes as a quick and reliable way to boost your outlook, relieve stress, and unwind. Smoking can also be a way of coping with depression, anxiety, or even boredom. Quitting means finding different, healthier ways to cope with those feelings. Smoking is also ingrained as a daily ritual. It may be an automatic response for you to smoke a cigarette with your morning coffee, while taking a break at work or on your commute home at the end of a hectic day. Or maybe your friends, family, or colleagues smoke, and it’s become part of the way you relate with them. To successfully stop smoking, you’ll need to address both the addiction and the habits and routines that go along with it. But it can be done. with the right support and quit plan, any smoker can kick the addiction—even if you’ve tried and failed multiple times before.

@bodhi Curd is defined as a product obtained by souring boiled or pasteurized milk naturally, by harmless lactic acid bacteria or other bacterial cultures. It may contain a wide variety of bacteria, which are not defined qualitatively/quantitatively. The number and type of bacteria also vary from home to home. While one cannot undermine the nutritional benefits that these products bestow, it still remains to be determined whether these products contain organisms that are defined in terms of number, viability at the target site and whether scientifically validated for health benefits (all these criteria as per the universally accepted probiotic definition). Hence, products that are standardized in terms of the strain of bacteria, viable count and scientifically proven health benefits are different from these natural products.