@abhila Chronic neuroinflammation secondary to either intrinsic or systemic stimuli is thought to play a key role in dementia development, especially Alzheimer's dementia (AD). Research showing a role of tumor necrosis factor–alpha (TNF-alpha) in the development of dementia has piqued interest in a potential protective effect of TNF inhibitors. "TNF-alpha is thought to have an important role in different stages of the pathophysiology and disease progression of Alzheimer's disease," study first author Sebastian E. Sattui, MD, assistant professor of medicine at the University of Pittsburgh and director of the University of Pittsburgh Vasculitis Center, said in an interview. "Animal models have shown that TNF inhibition reduces microgliosis, neuronal loss, and tau phosphorylation. Cognitive improvement has been seen in two trials with Alzheimer's disease patients, but were not in rheumatoid arthritis patients."
Latest posts made by Gagan deep
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RE: Reducing Inflammation May Lower Dementia Risk in RA
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RE: Does Eating Nuts Lead to Better Breast Cancer Outcomes?
@kunal Nuts are important components of healthy diets. Promoting this modifiable lifestyle factor should be emphasized in breast cancer survivor guidelines. The association for disease-free survival is quite strong and robust. However, as with all observational studies, this report shows an association and not causation.
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COVID-19 Virus May Prompt Body to Attack Itself
An international team of researchers studying COVID-19 has made a startling and pivotal discovery: The virus appears to cause the body to make weapons to attack its own tissues. The finding could unlock a number of COVID's clinical mysteries. They include the puzzling collection of symptoms that can come with the infection; the persistence of symptoms in some people for months after they clear the virus, a phenomenon dubbed long COVID; and why some children and adults have a serious inflammatory syndrome, called MIS-C or MIS-A, after their infections.
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RE: How to get rid of ear infection?
@debayan These methods are effective in relieving the symptoms of a mild ear infection:
Apply a warm cloth to the affected ear.
Take over-the-counter (OTC) pain medication such as ibuprofen (Advil) or acetaminophen (Tylenol).
Use OTC or prescription ear drops to relieve pain.
Take OTC decongestants like pseudoephedrine (Sudafed).
Avoid sleeping on the affected ear -
Is wearable device really a boon?
Hello, nowadays wearable devices are very common and people are using it for better monitoring of their health status. It provides the real time picture of the health, so that preventive measure or timely intervention can be convenient. Is wearable device really a boon? Please leave your comment.
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Home remedy to stop bleeding from finger cut rapidly?
Hello, my brother is 13 years old. He has got a finger cut. His bleeding is not getting stopped. My parents are out of station. So, me and my brother is alone. We are trying to stop bleeding, but it is not happening. Please suggest some home remedy to stop bleeding from finger cut rapidly.