Brain wave recordings obtained during cardiopulmonary resuscitation (CPR) offer support to near-death experiences subjectively reported by some people who survive cardiac arrest, according to a novel new study. These recalled experiences and brain wave changes may be the first signs of the so-called 'near-death' experience, and we have captured them for the first time in a large study

@somraj Investigators enrolled 296 sedentary men and women with MCI (mean age, about 75 years). All were randomly allocated to either an aerobic exercise group (maintaining a heart rate at about 70% to 85%) or a stretching and balance group (maintaining heart rate < 35%). Both groups exercised four times a week for about 30 to 40 minutes. In the first 12 months they were supervised by a trainer at the YMCA and then they exercised independently for the final 6 months.

Compared with vitamins, some dietary supplements increase the risk for severe medical events in youth, according to a study published online today in the Journal of Adolescent Health. Supplements sold for muscle building, weight loss, and energy were tied to about a threefold increase in risk for severe medical problems, including hospitalization and death.

Once again, strawberries and spinach, along with kale and collard and mustard greens, top this year's "Dirty Dozen" list, an annual and controversial ranking of nonorganic fruits and vegetables based on the amount of pesticides found in samples of the foods. The yearly report comes from the Environmental Working Group, a nonprofit organization dedicated to improving human health and the environment, and also includes a "Clean 15" list of produce. An industry group for growers of organic and nonorganic produce, along with some dietitians, make strong objections to the report, saying it raises unnecessary alarm and could discourage people from eating enough fruits and vegetables. The report gives people valuable information, says the Environmental Working Group's Alexis Temkin, PhD, a toxicologist, so they can make informed choices about the fruits and vegetables they buy.

An online visual test may identify patients with Parkinson's disease (PD) at highest risk for dementia, results of a new study suggest. The analysis showed that patients with PD did worse than controls on tests of specific aspects of visual processing related to object recognition, which could be a clue that cognition is affected.

@shipra The researchers analyzed 226 patients who underwent endovascular thrombectomy between January 2017 and February 2020 at four hospitals in the Mount Sinai health system using the NYC MIST Trial and a stroke database. At baseline, all patients were functionally independent as assessed by the modified Rankin Scale (mRS, score of 0-2). A total of 106 patients were treated by a MIST team — staffed by a neurointerventionalist, a fellow or physician assistant, and radiologic technologist — that traveled to the patient's location. A total of 120 patients were transferred to a comprehensive stroke center or a hospital with endovascular thrombectomy expertise. The analysis was stratified based on whether the patient presented in the early time window (≤ 6 hours) or late time window (> 6 hours).

Children with severe cow's milk allergy may be able to safely tolerate small amounts of baked milk after 12 months of oral immunotherapy, new research suggests. The small, ongoing clinical trial has enabled some participants — all of whom reacted to less than a tablespoon of baked milk at baseline — to begin incorporating baked milk products into everyday diets and to eat in restaurants with less fear of allergic reactions, reported study author Jennifer Dantzer, MD, MHS, an assistant professor of pediatrics in the Division of Pediatric Allergy, Immunology and Rheumatology at Johns Hopkins School of Medicine in Baltimore.

@jhilmil Polycystic ovary syndrome (PCOS) is a common multifaceted condition that is often associated with reproductive compromise (Dumesic et al., 2015) and, in particular, anovulatory infertility (Thessaloniki ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group, 2008; Legro et al., 2013). A wide range of effective interventions have been suggested for improving ovulation rates (Balen et al., 2016; Teede et al., 2018; Costello et al., 2019), even though the proportion of infertile patients with PCOS who undergo IVF is very high (Roos et al., 2011; Hart and Doherty, 2015; Rees et al., 2016; Mills et al., 2020). This discrepancy suggests other abnormalities that influence fertility among patients with PCOS, independent of ovulation. In addition, whether women with PCOS and normal ovulatory cycles, i.e. the ovulatory PCOS phenotype (Rotterdam ESHRE/ASRM-Sponsored PCOS consensus Workshop Group, 2004), have the same fertility of matched controls without PCOS is a matter of debate.

@amit-r Another problem is that some EpiPen devices may not slide out of the carrier tube easily, or at all, because of a slight deformation on the rim of the carrier tube. When this happens, the user may not be able to quickly remove the auto-injector from the carrier tube. This issue may affect any EpiPen auto-injector lot currently on the market in the US with an expiration date prior to September 2020. However, the likelihood of an auto-injector having this is "very low," the companies say. To be sure the device can be used when needed, pharmacists, patients, and caregivers should test that they can remove the device. Specifically, they should remove both carrier tubes from the S-clip, flip open the caps of the carrier tubes, and tip each carrier tube to make sure each auto-injector slides out easily.

Child sexual abuse (CSA) refers to the use of children (persons younger than 18 years old) in sexual activities when, because of their immaturity and developmental level, they cannot understand or give informed consent. A wide range of activities is included in sexual abuse, including contact and noncontact activities. Contact activities include sexualized kissing, fondling, masturbation, and digital and/or object penetration of the vagina and/or anus, as well as oral–genital, genital–genital, and anal–genital contact. Noncontact activities include exhibitionism, inappropriate observation of child (eg, while the child is dressing, using the toilet, bathing), the production or viewing of pornography, or involvement of children in prostitution. The sexual activities are imposed on the child and represent an abuse of the caregiver's power over the child. The sequence of activities often progresses from noncontact to contact over a period of time during which the child's trust in the caregiver is misused and betrayed.