@senjuti In fact, the American College of Rheumatology has added cognitive dysfunction to its list of diagnostic criteria for FM. However, the authors point out, this has proven difficult to study, in part because " 'executive functions' (EF) represent a multifaceted construct, composed of separable factors.... Considering EF as a whole would therefore not allow identification of subtle differences in cognitive complaints

@kankana The association between PTSD and PD in women was not significant. However, a 2017 study in a predominantly female cohort found a 3.46-fold increased risk for PD in patients with history of PTSD. The investigators note that emotional and physical stress have been linked to PD risk, although the causal association between stress or anxiety and PD has not been fully established.

Men with posttraumatic stress disorder (PTSD) have an increased risk of developing Parkinson's disease (PD) and need close monitoring for timely treatment, new research suggests. The risk is highest in men diagnosed with PTSD at age 72 or later, suggesting that PTSD in older men may be a prodromal symptom of Parkinson's, they suggest.

As previously stated, CPPS is, despite its name, a condition, not a disease or syndrome. It is similar to other chronic conditions, such as arthritis, that, while treatable, are not curable. No known cure exists for CPPS, but treatments based on the cooperation of patient and physician makes this condition more bearable. Over time, this condition may improve or stabilize on its own.

A new study suggests that increased levels of serum phosphate, but not calcium or vitamin D, could be a significant risk factor for incident aortic stenosis (AS). The findings were published in the European Journal of Preventive Cardiology . Calcific AS is the leading cause of mortality from nonrheumatic valvular disease, yet there is an unmet need for therapies that can slow down or arrest disease progression.

@nabamita It has been increasingly recognized that diet is a source of environmental factors that may contribute to bipolar disorder and other neuropsychiatric disorders. To investigate further, the researchers collected demographic, health, and dietary data on 758 adults aged 18 to 65 years who had been diagnosed with mania or other psychiatric disorders and a control group of 343 adults who had not been diagnosed with a psychiatric disorder. Food exposures were assessed using a questionnaire, developed by the research team, that asked participants whether or not they had eaten certain types of food.

In a study published online September 30 in The Lancet, investigators from the University of Cardiff in the United Kingdom say their findings, which show that ADHD has a genetic basis, suggest it should be classified as a neurodevelopmental and not a behavioral disorder.

A few studies of the impact of loneliness on endocrine disorders are starting to appear. A study from two military hospitals in Saudi Arabia identified a cohort of patients with treated hypothyroidism. The researchers administered a validated standard survey to assess the severity of loneliness. They found a correlation between duration of hypothyroidism and loneliness score. The prevalence of loneliness among their group of 231 levothyroxine users was 16%. The sample was small relative to the larger US and Chinese studies so it could not capture some of the widely accepted correlations with age and smoking. This study did not separate causes of hypothyroidism into autoimmune and postsurgical groups, nor did it distinguish between undertreated disease and therapeutic replacement therapy, so much remains to be explored.

Long or irregular menstrual cycles in relatively young women are linked an increased risk of both prevalent and incident nonalcoholic fatty liver disease (NAFLD), according to a cross-sectional study that included data on more than 70,000 women. The study evaluated women aged younger than 40 years who were participating in the Kangbuk Samsung Health Study, which involves a comprehensive biennial health examination at health centers in South Korea. Of the 135,090 women enrolled over a 6-year period who had at least one follow-up examination, 72,092 were available for analysis after excluding for a sizable list of confounding factors such as liver disease and infections; exposure to steatogenic medications, such as corticosteroids; hysterectomy; and pregnancy.

@aishee A review of the 29 cases underpinning the FDA's alert revealed that only seven met the Sternbach criteria for diagnosis of SS. To review, these criteria include:
Symptom onset with the addition of a serotonergic agent or an increase in the dose of a serotonergic agent that the patient is already taking
At least three of these physical findings are present: agitation, ataxia, diaphoresis, diarrhea, hyperreflexia, mental status changes, myoclonus, shivering, tremor, or hyperthermia
No recent addition of a neuroleptic agent to the patient's regimen or increase in dose of a previously prescribed neuroleptic agent