Results from a retrospective, observational, case-control study of more than 20,000 people from a single US medical center showed a statistically significant but clinically insignificant increase in A1c in people following COVID-19 infection, in both those with and without diabetes. After people received a diagnosis of COVID-19 infection they were 40% more likely to also receive a diagnosis of type 2 diabetes compared with people who tested negative for COVID-19, a difference that was significant and could be explained by the increased medical care received by people who test positive for COVID-19. The risk of incident diabetic ketoacidosis (DKA) among people who tested positive for COVID-19 was significantly higher among those with preexisting type 2 diabetes, those using insulin, and among Black individuals.

@koli The prognosis in patients with ADPKD covers a wide spectrum. Kidney failure has been reported in children; conversely, individuals with ADPKD may live a normal lifespan without knowing that they have the disease. More typically, however, ADPKD causes progressive kidney dysfunction, resulting in grossly enlarged kidneys and kidney failure by the fourth to sixth decade of life. There is an inverse association between the size of polycystic kidneys and the level of glomerular filtration.
An early study estimated that approximately 70% of patients with ADPKD would develop kidney insufficiency if they survived to age 65 years. Currently, half of all patients with ADPKD require renal replacement therapy by age 60 years. Risk factors for progression include the following:
PKD1 genotype
Large kidneys
Several episodes of gross hematuria
Severe and frequent kidney infections
Hypertension
Multiple pregnancies
Black racial background
Male sex

India is currently battling the third wave of the novel coronavirus disease (COVID-19), triggered by the high infectious omicron variant. Medical experts have warned that past mistakes, especially regarding treatment, must not be repeated. Is there any home remedy to cure omicron infection?

A 58-year-old female patient was activated as a Level 1 trauma alert after being involved in a house explosion with resultant fire. She was awake and alert with no loss of consciousness at the scene but sustained significant thermal injuries. She was intubated pre-hospital for “airway protection” out of concern for inhalation injury with facial burns. Initial evaluation revealed an older woman, orally intubated with bilateral breath sounds, mildly tachycardic in the 100s, moderately hypertensive in the 160s/90s, with readily apparent full-thickness burns to the face, neck, anterior torso, bilateral arms, and bilateral legs. Please recommend some management for burn.

Hello, my 19 year old university student was admitted to our hospital with history of high grade swinging temperature up to 39°C. She had had a sore throat, which lasted for a few days, accompanied by fever, rigors, and myalgia. Her general practitioner prescribed amoxicillin, and she subsequently developed a macular rash on her wrists, back, and legs associated with the fever spikes. The symptoms were persistent over three weeks, prompting referral to our department. She had travelled to Italy recently and recollected being bitten by mosquitoes. She had no history of recreational drug use or sexual contact and she was not taking any regular medication. Please suggest what should we do?