@pritha According to a large population-based study conducted in 2016, there is no significant link between exposure to general anesthesia and the development of MCI in individuals aged 40 years and older. Anesthesia exposure, assessed as a dichotomous variable, was not associated with MCI nor was there was a link between the number of anesthesia exposures and MCI.

Between 2014 and 2020, the frequency of adverse pregnancy outcomes in the United States increased among women with gestational diabetes, with persisting differences in adverse outcomes by race and ethnicity, according to a report in JAMA. Population-based studies on racial and ethnic disparities in gestational diabetes have focused on differences in the rate of diagnosis, rather than adverse pregnancy outcomes. The researchers conducted a cross-sectional, descriptive study to evaluate whether the frequency of adverse pregnancy outcomes with gestational diabetes changed over time and whether the risk of these outcomes differed by maternal race and ethnicity. The data were obtained from the Centers for Disease Control and Prevention’s National Center for Health Statistics Natality Files. Exposures of interest were year of delivery, as well as race and ethnicity.

Eating nitrate-cured meats such as beef jerky and other processed meat snacks has been strongly linked to an increased risk for mania, new research shows. A study of roughly 1100 adults showed that those who were hospitalized for a manic episode were more than three times more likely to have ever eaten nitrate-cured meats than those who did not have a history of a serious psychiatric disorder.

@senjuti It's estimated that about 2.8 million people in the United States receive medical care each year for a TBI, primarily as a result of road accidents, falls, assault, and sports injuries. Mild TBIs account for 80% to 95% of these cases. They are difficult to diagnose because routine tests, including imaging, fail to show changes in brain structure. Patients with TBI can experience behavioral, emotional, and cognitive impairments that could include memory and concentration deficits, poor executive function, depression, and anxiety. The brain trauma is also a risk factor for diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). There is currently no proven effective treatment for TBI.

Aerobic exercise may help reduce blood pressure in patients whose hypertension responds poorly to medications, a new study suggests. A randomized controlled clinical trial showed that patients with resistant hypertension assigned to a moderate-intensity aerobic exercise training program had lower blood pressure (BP) compared with patients who received usual care. Resistant hypertension persists as a big clinical challenge because the available treatment options to lower blood pressure in this clinical population, namely drugs and renal denervation, show limited success.

@priyam Medical therapy
Nonoperative therapy is reserved for minimally displaced favorable fractures. Children often incur an incomplete fracture called a greenstick fracture, which is amenable to conservative therapy. Elderly edentulous patients with minimal displacements can be treated in a similar manner.
Surgical therapy
Closed reduction maintains the segments by maxillomandibular fixation. Open reduction allows for direct evaluation of the mandibular segments and further for internal or external fixation; it necessitates a mucosal or skin incision for direct access to the fracture site.
Internal fixation can be accomplished by wire (used more historically and in children), titanium plate, and screw fixation.
External fixation was popular in World War II but currently is not often employed. Principle indications are sites that have been infected or pathologic fractures. It can also be used in edentulous patients with unstable fractures. Stainless steel pins and composite resin placed lateral to the mandible keep the fracture rigidly reduced.

@poulami As the population ages, the number of individuals experiencing age-related conditions, including dementia, increases. There is no cure for most dementia types so prevention is key — and preventing dementia requires understanding its risk factors.

Hello, What is Pott disease? Is it a serious condition? Can it be cured ? One of my distant relatives got this problem. He is 45 years old and living alone. That is the reason it is a matter of concern. Please leave your comments on this.

A patient presented with acute severe pain from the upper right quadrant. It was poorly localized, and the patient stated that the pain radiated into the ear and the cheek on the right-hand side. Pain was spontaneous and not responding well to over-the-counter analgesics (Ibuprofen 400mg), and had been gradually getting worse over the last 48 hours. The patient was experiencing sleep disturbance, and the pain came on in waves. There was extreme sensitivity to cold stimulus, but not so painful with hot stimulus. He was diagnosed with pulpitis. Please recommend some treatment for pulpitis.

Hello, my friend is a 44-year-old woman with two children. She initially presented at age 41, complaining of stress urinary incontinence (SUI) with coughing and exercise. At that time, she was wearing pantiliners on a daily basis for protection against frequent incontinent episodes. She is now 44 years old and her overall health continues to be good. However, she is once again experiencing SUI with exercise and coughing. The frequency is approximately every two hours during the day and averages twice nightly. This is having a considerable deleterious impact on her quality of life, as she is very active in sports and again has to wear pantiliners most of the time for protection and maxi pads during exercise. Please advise what should she do.