@sagnika Published Monday in JAMA Network Open, the study involved 551,388 U.S. participants using information collected by the CDC from 1997 to 2018. Researchers collected data for specific causes of death of participants through the end of 2019. The results echo past findings but also established whether demographic factors such as a smoker's race and gender impact the benefits of quitting. (In many areas of health research, a person's race or gender is associated with varying risks.)

The latest upward trend in new COVID-19 cases among children picked up steam, but there was also some movement in the vaccination effort in the past week. Moderna submitted a request to the Food and Drug administration for emergency use authorization of its COVID-19 vaccine in children under the age of 6 years, according to this news organization, and Pfizer/BioNTech officially applied for authorization of a booster dose in children aged 5-11, the companies announced.

@khushboo In animal models, levels of A muciniphila, one of the most abundant bacteria of the gut microbiota, were inversely correlated with body weight, adiposity, blood glucose, and intestinal permeability. Administration of A muciniphila to mice receiving a high-fat diet was associated with an increase in the mucus layer and restoration of the expression of tight junction proteins, antimicrobial peptides, and bioactive lipids with anti-inflammatory properties. A muciniphila also was associated with a decrease in obesity, inflammatory parameters, and insulin resistance and an improvement in glucose tolerance.

More than 40 medical conditions were positively associated with having a new diagnosis of osteoarthritis according to research presented at the OARSI 2022 World Congress. The results are very interesting starting points for future research, because of course, this was an explorative study.

@khushboo Ethanol is a small molecule that readily distributes to the brain and reaches peak levels in blood approximately 30 minutes after ingestion of an alcoholic drink. Ethanol affects proteins that are associated with a wide variety of neurotransmitters and pathways. These include the dopamine pathway, serotonin pathway, proteins associated with GABAA receptor, glutamate receptors (ie, N -methyl-D-aspartate [NMDA]/α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid [AMPA]/Kainate), mGlu receptors, nicotinic receptors, cannabinoid CB1 receptors, voltage-gated calcium ion channels, and calcium-activated potassium channels. Like other psychotic disorders, the exact etiology of alcohol-related psychosis remains unclear, but most likely it is related to dopamine in the limbic and possibly other systems, such as the glutamatergic neurotransmitter system. The dopamine hypothesis often is applied to psychosis involving excessive activity of the dopaminergic system. Animal studies have shown dopaminergic activity to increase with increased release of dopamine when alcohol is administered.

@rajan Amino acids are known as the building blocks of protein, which is an important component of every cell in your body. Athletes commonly use leucine, isoleucine, and valine to improve their performance. These amino acids can be metabolized in muscle to provide extra energy during exercise. Research suggests that taking amino acid supplements during recovery days after exercise reduces muscle damage as well as the soreness that comes along with it. Evidence suggests that taking branched-chain amino acids by mouth can improve liver function in people with poor brain function due to liver disease.

@mukund In a significant breakthrough in treatment of diabetics, the scientists in Bangalore have found that cow urine reduces the blood sugar level. A study conducted by Professor K Jayakumar of the Government Veterinary College Bangalore has shown that cow’s urine has anti-diabetic properties. It is to be investigated whether cow’s urine stimulates beta cells, as in the case anti-diabetic agents available in the market. The activity was tested in experimentally induced diabetic rats. The rats were orally given a small dose of cow’s urine daily. It was noticed that rats treated with the cow’s urine had lower Blood-sugar level as compared to non -treated diabetic rats

@anwesha The following is an outline of the program of treatment that can be designed for your neighbor.

• Hydrotherapy – 10 to 15 minutes four to six times daily.
• Gentle soft tissue and stretching techniques.
• Rest – Important to outline the mechanism of injury and how to avoid it.
• Pain Relief & Non-steroidal anti-inflammatory drugs (NSAID’s).
• Workstation advice and assessment.

@kevin Tulsi is a member of the mint family and its traditional medicinal uses are many, particularly in Ayurvedic tradition. Holy basil, or tulsi, leaves are widely used to prepare desi concoctions to treat microbial infections and boost immunity. It does not only possess antiseptic and analgesic properties that help cure many problems including dry cough, but a tea made using with tulsi leaves relieves allergic bronchitis, asthma and other lung diseases in no time. It also has immunomodulatory (to enhance immunity) and antitussive (relieves cough) properties that provide relief in the respiratory system. In fact, it has certain oils that may clear the congestion.

@Tanisha Lifestyle modification is critical to prevent or delay serious health consequences associated with PCOS, and it should be initiated in all overweight women with the syndrome. Diet and exercise are two of the best initial options to restore fertility and alleviate symptoms in obese women with PCOS. Clinical trials suggest that a diet low in saturated fats and high in dietary fiber with low-glycemic-index carbohydrates is preferred. A study conducted by Huber-Buchholz et al. evaluated the effect of a six-month diet and exercise program in 28 obese women with PCOS who were trying to become pregnant or restore menstrual regularity. Study results demonstrated that with a mean weight loss of 2% to 5%, women were able to reduce central fat by 11%, improve their insulin sensitivity index by 71%, reduce fasting insulin levels by 33%, and reduce LH by 39%. Of the 15 an ovulatory women enrolled in the study, nine regained regular ovulation and two became pregnant. If lifestyle modification fails to reach treatment goals, pharmacologic agents may be used.
Hirsutism is commonly managed with cosmetic hair removal procedures. Women may elect to use laser hair removal, electrolysis, bleaching, depilatory agents, waxing, or shaving. When performing a patient interview, it is important to inquire about a history of excessive, male-pattern hair growth, as hirsutism may be improved or absent due to cosmetic removal.
An additional therapeutic intervention that may be used for ovulation induction is the surgical procedure laparoscopic ovarian drilling, although its use has declined since the 1990s with the introduction of equally effective pharmacologic agents.