@lata ETI has significantly altered CF care by its ability to restore CFTR function to almost normal. This leads to improvement in lung function and quality of life while reducing pulmonary exacerbations and hospitalization. The study suggests that increased excretion of bicarbonate by the kidneys appears to reflect that improvement, according to the researchers.

@xio Class Summary
The mechanism of action of antifungal agents usually involves the alteration of the permeability of the cell membrane (polyenes) of the fungal cell or the inhibition of pathways (enzymes, substrates, transport) necessary for sterol/cell membrane synthesis.

Miconazole topical (Desenex Spray, Lotrimin AF, Baza Antifungal, Carrington Antifungal, Micaderm, Micatin)
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This agent damages the fungal cell wall membrane by inhibiting the biosynthesis of ergosterol. By increasing membrane permeability, it causes nutrients to leak out of the cell, resulting in fungal cell death. Lotion is preferred in intertriginous areas. If cream is used, it should be applied sparingly to avoid maceration effects.

Ketoconazole (Nizoral, Extina, Xologel)
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Ketoconazole has fungistatic activity. An imidazole with broad-spectrum antifungal action, it inhibits the synthesis of ergosterol, causing cellular components to leak and resulting in fungal cell death.

Itraconazole (Sporanox, Onmel)
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This is a synthetic fungistatic triazole that inhibits cytochrome P-450–dependent synthesis of ergosterol, a vital component of fungal cell membranes.

@uana Hello, hair fall after menopause is common and many women suffer from the same. Menopause, and the years following it, can impact hair health in numerous ways.

• Talk to healthcare professionals sometimes other conditions like adrenal imbalances, hypothyroidism, or vitamin deficiencies are to blame.
• Maintain a healthy diet and eat quality protein, and foods rich in omega 3s, vitamins C, A, and E, iron, zinc, selenium, and biotin.
• Exercise- Increase the circulation to your scalp. Do yoga and aerobics the blood flowing to your scalp, and thus nourish your precious roots.