Radiotherapy for painful bone metastases is a standard of care, but a new study that looked at earlier use of the modality had an unexpected result. It showed that prophylactic radiotherapy given to patients with cancer and asymptomatic bone metastases not only reduces skeletal-related events and hospitalizations, but also offers a survival benefit. In the first study of its kind, almost 80 patients with more than five high-risk metastases were randomly assigned to receive either prophylactic radiotherapy or standard care.

Devices that help children control their diabetes and lead fuller lives may also give them contact dermatitis, report the authors of a new study that calls for mandatory labeling of ingredients for allergy patch testing. A high share of patients showed positive reactions to isobornyl acrylate adhesive (IBOA) and/or their medical devices (insulin pumps or glucose devices)," the study authors write in Contact Dermatitis. "A third of patients showed positive reactions to benzoyl peroxide (BP)," used in adhesives.

@harish Results from the new randomized, open-label, two-period crossover study comparing the two insulins were presented by Thomas Pieber, MD, on June 5 at the American Diabetes Association (ADA) 82nd Scientific Sessions. In the study, insulin icodec once weekly for 6 weeks was compared with glargine U100 once daily for 11 days, with single evaluations of doubling and tripling the doses during those periods. There were no differences in hypoglycemia between the two insulins, although some differences were found in other hormonal responses, said Pieber, who is head of the division of endocrinology and metabolism at the Medical University of Graz, Austria.

Increased screen time among children during the COVID-19 pandemic has led to a potential risk of health problems ranging from eye issues to back and neck problems and even obesity. Children and adolescents often use several devices at once; the practice increases the strain on the eye by 22%. Potential problems include unstable binocular vision as they attempt to adjust between screens, uncorrected refractive error, and dry eyes, as well as neck and shoulder strain; in addition, a sedentary lifestyle may lead to obesity. The COVID-19 pandemic led to the unprecedented shutdown of schools across the globe, causing many students to rely on digital devices to continue with their education. Significant increases in screen time across the globe include a more than double the use of screens by toddler and preschool children in Chile, an 89% increase in Canada, and an unprecedented increase of 111% for children aged 5–12 in Tunisia.

@harish Prevention of type 2 diabetes, as well as prevention of diastolic dysfunction development and progression, are key steps because of the substantial clinical consequences of diastolic dysfunction, triggered by stiffening of the left ventricle. Diastolic dysfunction leads to increased left ventricular diastolic pressure, left atrial dysfunction, and ultimately heart failure with preserved ejection fraction, a common diabetes complication that currently has no treatment with proven efficacy, said Dr. Shah, a pediatric endocrinologist and director of the Adolescent Type 2 Diabetes Program at Cincinnati Children's Hospital Medical Center.

A vegetarian or vegan diet is said to be particularly popular among girls and young women. But despite what some people think, these diets, especially vegan diets, are not automatically healthy. A vegan diet can lead to nutritional deficits as a result of the limited choice of foods. These deficits can cause clinically relevant symptoms if they are not balanced out. One of the things to keep in mind is the need for a sufficient amount of vitamins B12 and B6, as well as vitamin D. Another diet is the orthorexic diet. Followers of this diet force themselves to have a healthy diet and are afraid of getting sick from unhealthy food. As the nutritional scientist explains, orthorexic persons set their own definitions of what is healthy. While some refrain from certain foods (eg, household sugar), others eliminate whole food groups and eat nothing but raw food. Compulsive behavior can appear in specific methods of food preparation or adherence to fixed meal schedules.

Exposure to air pollution — even short term — may play a role in triggering psoriasis flares, according to new research from Italy, which found a significant association between exposure to higher levels of air pollution prior to patients presenting for psoriasis flares at medical visits, compared with visits unrelated to flares. The findings underscore the need for clinicians to "consider environmental/external triggers in patients with chronic inflammatory diseases experiencing flares

Nearly 20 to 30% of the population have the habit of nail biting — but the seemingly innocuous behavior is actually not as harmless as you might think. When left untreated, chronic nail-biting can lead to a slew of health problems, including infections and other hygiene issues (not to mention you'll never get those dream nails you always wanted!). How to get rid of rid of the habit of nail biting?

Hello, Presbyopia is the gradual loss of your eyes' ability to focus on nearby objects. It's a natural, often annoying part of aging. Presbyopia usually becomes noticeable in your early to mid-40s and continues to worsen until around age 65. How to manage this condition? Please leave your comments.

@nimmy Treatment for psychosis involves a combination of antipsychotic medicines, psychological therapies, and social support. Your treatment is likely to involve a team of mental health professionals working together. If this is your first psychotic episode, you may be referred to an early intervention team. An early intervention team is a team of healthcare professionals set up specifically to work with people who have experienced their first episode of psychosis.
Depending on your care needs, early intervention teams aim to provide:
a full assessment of your needs
medicine
psychological therapies
social, occupational and educational interventions