Self-management of gout using a smartphone app to record self-test urate levels and flares, and communicate those results to clinicians, could see more patients reaching target urate levels and even reducing flare frequency, a study has found.

Writing in The Lancet Rheumatology, Philip Riches, PhD, of the rheumatic disease unit at Western General Hospital in Edinburgh, and coauthors presented the findings of their randomized, controlled feasibility study of a new gout self-management approach aimed at helping patients treat to target.

Neoadjuvant immunotherapy for stage II-IV cutaneous squamous cell carcinoma (CSCC) led to a strong pathological complete response rate, according to results from a stage 2 clinical trial. CSCC hasn't received much attention from pharmaceutical companies, in part because it so often responds well to surgery or local therapy. Still, some patients develop more advanced cancer that requires surgery, often on exposed surfaces like the scalp, face, or neck. That can lead to cosmetic and functional impairment.

@kinjal More research is needed to determine how best to achieve depression remission in those patients with less than 7 hours of objective sleep prior to starting treatment. It's important to remember that sleep comes from our brain and so does our mood and emotional regulation and irritability. So if one part of it isn't quite doing what it's supposed to be doing, it certainly can throw the other part off too.

@cherry The most discreet small hearing aids include custom "in the ear" (ITE) styles, such as "completely in the canal" (CIC) and "invisible in the canal" (IIC). Both of these types fit deep inside the ear canal, hidden in the contours of the ear. Although social stigmas may have you leaning toward smaller, more discreet custom devices, these models aren’t suitable for everyone. These devices are as close to being invisible as they get. There are no external tubes or wires. Because they are lightweight and custom molded to fit inside your ear canal, they are comfortable for most wearers. These small hearing aids aren't suitable for people with severe, more advanced hearing loss. They work best for mild to moderate losses. If your hearing loss is worse than that, you may hear better wearing a behind the ear (BTE) model, which can pack more power inside. They don’t fit in everyone’s ear canal. Those with short or differently-shaped ear canals can’t wear them.

Hello, I am 35 years old. I have no medical history of illness. I regularly drink 30 ml of alcohol for keeping my cardiovascular health fit and fine. I went to a party two days back. I am having diarrhoea today. I drank a lot yesterday. Is it due to my excessive drinking? I cannot figure this out. Please explain why do I get diarrhoea after drinking alcohol?

Hello, an 18-year-old girl, a resident of Lucknow (Uttar Pradesh State), presented with chief complaints of multiple, nodulo-ulcerative lesions over arms and painful reddish nodular lesions over both legs and abdomen of 7 months duration. Patient was apparently well till 7 months back when she noticed painful nodules over the arms. The nodules were initially red in color. Ulcerative erythema nodosum- how to cure?