Though HIV continues to be a plague 40 years on, for several reasons monkeypox is unlikely to become as significant. HIV establishes a chronic infection with high mortality if untreated, and a practical preventive approach through vaccination has been elusive. Orthopox, on the other hand, is an acute infection with very low mortality. The transmissibility appears nowhere near SARS-CoV-2 and differs from HIV because it has a fairly short infectivity duration. Many infected with monkeypox acquired infection after participation in multiple sexual encounters. An early estimate of the 2022 outbreak places the R0 number at 1.29, with a higher rate in the United States, at 1.55. These numbers are concerning because they're greater than 1, but if they hold, they will still be nowhere near those of SARS-CoV-2 or HIV. For these reasons, the World Health Organization suggested limiting the number of sexual partners in the current environment.
Latest posts made by Satyajit
Monkeypox and HIV: Same but Different?
New Science Behind Speech Impairments in Parkinson's Disease
This study suggests and integrates new methods of spectral brain mapping and speech impairment quantification to characterize the functional neural pathology that plays a role in speech impairment in Parkinson's disease (PD). In a large group of patients with PD, a pathological relationship between articulation impairments and spectral deviations in the left inferior frontal cortex (LIFC) was identified, especially in the alpha and delta bands. In healthy adults, the LIFC is a focal point that features multifrequency interactions with a number of language network regions. The more significant the spectral deviations in the LIFC, the more evident the articulation deficits in patients with PD.
The Gut a New Therapeutic Target for Brain Disorders?
Changes in the mucus that lines the gastrointestinal (GI) tract may contribute to bacterial imbalance in the gut and exacerbate core symptoms of autism, Parkinson disease (PD), Alzheimer disease (AD), and multiple sclerosis (MS), new research suggests.
Biomarkers Predict Cardiovascular Risk in Chronic Kidney Disease Patients
Models using novel kidney and cardiac biomarkers were the most effective predictors of 10-year risk for atherosclerotic cardiovascular disease in chronic kidney disease patients, in a new study. Chronic kidney disease (CKD) patients may be at increased risk for atherosclerotic cardiovascular disease, but no ASCVD risk prediction models are currently in place to inform clinical care and prevention strategies, Joshua Bundy, PhD, of Tulane University, New Orleans, and colleagues wrote in their paper, published in the Journal of the American Society of Nephrology.
What are the prehospital care in case of dog bite?
It is a fact of life that dogs bite. Approximately 4.7 million bites inflicted by dogs on people are reported in the US every single year. Although these statistics sound grim, at least 80% of these bites only result in minimal injury and can be treated by someone with basic first aid training. Please suggest some prehospital care in case of dog bite.
RE: What should be avoided in hypothyroidism?
@arpan Avoid or limit added sugars, highly processed foods, and foods high in saturated fats
This is especially important for people who have Hashimoto's thyroiditis
These foods may increase cholesterol
void grapefruit or grapefruit juice, coffee, foods that contain soy or cottonseed meal, walnuts, or dietary fibers for at least four hours after taking hormone replacement medication, such as levothyroxine (Synthroid, Levoxyl, Levothroid, Unithyroid) as these foods may impact how the body absorbs the medication or decrease its potency
Foods high in fiber, high in calcium, or high in iron may lower the effective dosage of thyroid medication when eaten within four to five hours of taking thyroid medication
Is there any male contraception method ?
Hello, Is there any male contraception method ? I am only aware of female contraception. In the past 50 years, there have been few changes in male contraception compared with the range of options available to women. Please leave your comments on this.
How to make my hair healthy during winter?
Hello, I would like to know how to make my hair healthy during winter. My hairs are becoming frizzy. During winter I can not wash my hair frequently. That might be the reason. Please help me and provide some recommendations.
Systemic amyloidosis- what is this?
A 50-year-old female patient without the history of any diseases was admitted to hospital. She had difficulties in squatting for 5 years, impaired tongue movements, coarseness and dysphagia for 8 months, extensively tightened and pigmented skin for 6 months. She felt tingling when touching cold water and warming up hands relieved the symptom. The symptom kept progressing to the point where the skin became so extensively tightened that the movements of lower limbs were significantly restricted. Constitutional symptoms included low fever, fatigue, joint pain, and morning stiffness. She once visited a physician at local hospital where she was diagnosed as scleroderma. She was treated with traditional Chinese medicines and very little improvement was achieved. Two years ago, she had snoring and apnea during sleep and was diagnosed as obstructive sleep apnea hypopnea syndrome, but she refused noninvasive ventilation. Eight months ago, she visited a neurologist in other hospital due to difficulty in opening mouth and moving tongue, dysphagia, hoarseness, and ever-worsening skin tightness. Brain magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) showed bilateral lacunar infarction of basal ganglia, white matter demyelination in mild cerebral, multiple sclerosis in cerebral arteries, and mild stenosis of bilateral posterior cerebral artery. Neuro-electrography revealed mild to moderate demyelinating peripheral neuropathy and the damage in the left pyramidal tract. Polysomnography revealed a moderate obstructive sleep apnea-hypopnea syndrome and mild hypoxemia. She was then diagnosed as extrapyramidal disease and sleep apnea-hypopnea syndrome, and treated with madopar tablet and neurotropin. However, no evident effect was observed
Pediatric febrile seizures- treatment option?
Hello, I am a school teacher. My colleague's 8 month girl, fully immunized suffered from sudden seizure activity. Parents report 4 days of fever but no respiratory or GI symptoms. She has a history of febrile seizures as a toddler. The baby was fatigued, alert, no distress or signs of dehydration. Vitals within normal limits, temp 37.4, normal capillary refill and color. Her respiratory, abdominal and ENT exams are unremarkable. Her neck is supple and the neurological exam is normal. What are the treatment options for pediatric febrile seizures?