Higher levels of air pollution were associated with an increased risk for amyloid-beta pathology in a new study of older adults with cognitive impairment. The investigators used data from the IDEAS study to assess the relationship between the air quality at the place of residence of each patient and the likelihood of a positive amyloid PET result. Public records from the US Environmental Protection Agency were used to estimate air quality in individual ZIP-code areas during two periods ― 2002 to 2003 (approximately 14 years before the amyloid PET scan) and 2015 to 2016 (approximately 1 year before the amyloid PET scan).

Lithium could be linked to a decrease in the risk of developing dementia for some people, according to a small study. Researchers at the University of Cambridge described their preliminary findings as "promising" and said that they justified conducting larger, randomised trials to test the results. Lithium has been proposed as a possible preventative treatment for dementia, but little population-level research has been conducted to support the idea that its use might delay onset

@papiya However, there are currently no universal guidelines on how large an AI dataset needs to be to yield accurate results. In the dermatology literature, most AI datasets range between 600 and 14,000 examples with a large study-specific variation in performance. Misleading results can result from unanticipated training errors. The AI network may learn its intended task or an unrelated situational cue. For example, you can use great images to predict melanoma, but you may have an unintended poor outcome related to images that have, say, a ruler inside of them clustered within the melanoma diagnoses.

The term hypertensive nephrosclerosis has traditionally been used to describe a clinical syndrome characterized by long-term essential hypertension, hypertensive retinopathy, left ventricular hypertrophy, minimal proteinuria, and progressive kidney failure. Most cases are diagnosed based solely on clinical findings. In fact, most of the literature dedicated to hypertensive nephrosclerosis is based on the assumption that progressive kidney failure in a patient with long-standing hypertension, moderate proteinuria, and no evidence suggesting an alternative diagnosis characterizes hypertensive nephrosclerosis.

Hello, I have got tanning on my wrist due to regular use of watch. How to remove watch tan? Please provide some suggestions on how to get rid of this. Please help.

Hello, What is the use of capreomycin? and what are the side effects of this. How does this medicine work? What is the route of administration? Please elaborate on this.

@anushtup Research shows that headaches become more common in the winter season as cold temperatures and short sunshine duration can alter the atmospheric (barometric) pressure. This change in pressure can cause haemodynamic (internal blood pressure mechanism) changes in the body, leading to headaches or migraines. Also, the chilly winter winds can constrict the nerves and blood vessels in the brain, which can also lead to headaches. Following are some simple tips to keep in mind during the winter season to avoid frequent headaches:
Cover your head and neck with proper winter clothing before stepping out on a cold day.
Keep your neck and shoulder muscles relaxed for proper blood circulation. If you feel tense, try massaging, stretching the muscles and doing gentle circular movements of the neck.
Get eight good hours (at a stretch) of sleep regularly. Also, try to maintain a sleep pattern by sleeping and waking up at the same time every night.
Keep the room warm by using a radiator. You can also use a humidifier if you feel your room isn’t humid enough.

@tithi It's normal for kids to feel sad, act grouchy, or be in a bad mood at times. But when a sad or bad mood lasts for weeks or longer, and when there are other changes in a child's behavior, it might be depression. Therapy can help children who are going through sadness or depression. And there are things parents can do, too. Getting the right care can prevent things from getting worse and help a child feel better. If sadness has lasted for weeks or longer, talk about it with your child's doctor. Depression can drain a child's energy. They might put less effort into school than before. Even doing little tasks can feel like too much effort. Kids may seem tired, give up easily, or not try.

@mitali Adequate protein intake is critical for health and development. Generally, protein of animal origin is of higher quality for humans owing to its amino acid pattern and good digestibility. When administered in mixtures it can enhance the quality of plant proteins, but its availability is often low in low-income communities, especially in young children, the elderly, and pregnant and lactating women, who have increased requirements and in whom high-quality protein also stimulates (bone) growth and maintenance. Although high protein intake was associated with increased type 2 diabetes mellitus risk, milk and seafood are good sources of branched chain amino acids and taurine, which act beneficially on glucose metabolism and blood pressure. However, high consumption of protein-rich animal food is also associated with adverse health effects and higher risk for noncommunicable diseases, partly related to other components of these foods, like saturated fatty acids and potential carcinogens in processed meat but also the atherogenic methionine metabolite homocysteine. In moderation, however, animal proteins are especially important for health maintenance in vulnerable persons.

Hello, my grandfather is suffering from acute severe asthma. He has got worsening trouble breathing and wheezing, fast breathing, worsening cough and chest tightness, inability to breathe when laying down, trouble walking and talking, sweating. What should we do?