A noninvasive wearable nerve stimulator improves pain to the point of needing less analgesia in patients with neuropathy, arthritis, and other common forms of chronic pain, a new study shows. The stimulator, inserted into a slim, lightweight band and worn on the upper calf, stimulates sensory nerves, which carry neural pulses to the brain. The pulses trigger release of endogenous opioids within the spinal cord.

@sarmistha This patient's diagnosis of polyglandular failure type I was made on the basis of her peculiar clinical presentation (her history of oral ulcers, hyperpigmentation, postural drop in blood pressure, and significant family history) and the pertinent laboratory findings of decreased cortisol levels, elevated adrenocorticotropin level, and evidence of candidiasis on oral mucosal swab. Polyglandular autoimmune syndromes (PGA) are rare immune endocrinopathies characterized by the coexistence of at least 2 endocrine gland insufficiencies that are based on autoimmune mechanisms. Associations with nonendocrine immune diseases also occur. PGA can be classified as type I (PGA-I) and type II (PGA-II), which is more common and is also known as Schmidt syndrome. A third type (type III) occurs in adults and does not affect the adrenal cortex, but does include 2 of the following: thyroid deficiency, pernicious anemia, type 1A diabetes mellitus, vitiligo, and alopecia

Although the terms decubitus ulcer, pressure sore, and pressure ulcer have often been used interchangeably, the National Pressure Injury Advisory Panel (NPIAP; formerly the National Pressure Ulcer Advisory Panel [NPUAP]) currently considers pressure injury the best term to use, given that open ulceration does not always occur. According to the NPIAP, a pressure injury is localized damage to the skin and underlying soft tissue, usually over a bony prominence or related to a medical or other device. It can present as intact skin or an open ulcer and may be painful. It occurs as a result of intense or prolonged pressure or pressure in combination with shear.

@keka Legislation that limits abortion access to the days before fetal cardiac activity may make abortion unequally accessible. Because of differences in menstrual regularity, 'heartbeat bills' are likely to limit access to abortion for young people, Hispanic people, and people with common medical conditions for physiological reasons over which people have no control

The term protoporphyria now encompasses two clinically similar disorders that most often result from hereditary mutations in one of three different genes. The most common is erythropoietic protoporphyria (EPP). It is an inherited disorder caused by partial deficiency in mitochondrial ferrochelatase (FECH), the terminal enzyme of heme biosynthesis. The resultant accumulated excess of its substrate, metal-free protoporphyrin, causes two principal manifestations: (1) an acute cutaneous photosensitivity typically first appearing during childhood and (2) hepatobiliary disease

Hello, it's been 15 years since my father became diabetic. My father's fasting blood sugar is deranged, but PP is normal. What is the reason behind? What should be the method of treatment? Please leave your comments.

Hello, my father is 56 years old. He has been suffering from diabetes for last ten years. Now he needs to be shifted on insulin. Oral hypoglycemic drugs can not normalize his blood sugar level. Doctor has suggested for continuous glucose monitoring devices. Is continuous glucose monitoring (CGM) effective to monitor diabetes? Please explain.

A 20-year-old black male patient, with sickle cell disease, was admitted following a vasoocclusive episode. Therapy with intravenous fluids, analgesics, supplemental oxygen and antibiotics was done. In the 7th day of admission, the patient developed fever, dyspnea and hypoxemia. Investigation showed worsening anemia (decrease in hemoglobin from 7.9 to 5.3 g/dL) and hemolysis, with increased inflammatory markers. Chest computed tomography revealed bilateral, homogeneous, lung condensation and pleural effusion. How to treat this?