Sport climbing can help improve posture in patients with Parkinson's Disease (PD), including older patients, new research suggests. In a randomized controlled study, those who participated in scaling a wall using ropes and fixed anchors were less stooped at 12 weeks than a control group that participated in some form of unsupervised physical activity.

@miraj The risk for depression or clinically relevant depressive symptoms (total of incident and recurrent cases) was not significantly different between the vitamin D3 group (609 depression or clinically relevant depressive symptom events; 12.9/1000 person-years) and the placebo group (625 depression or clinically relevant depressive symptom events; 13.3/1000 person-years). The hazard ratio was 0.97 (95% CI, 0.87 – 1.09; P = .62).

@zeenam When physicians experience burnout, they are not able to deliver the best care for patients and start to disengage from the healthcare community, which may lead academic physicians to leave the academy or community physicians to reduce hours or retire early

This study suggests and integrates new methods of spectral brain mapping and speech impairment quantification to characterize the functional neural pathology that plays a role in speech impairment in Parkinson's disease (PD). In a large group of patients with PD, a pathological relationship between articulation impairments and spectral deviations in the left inferior frontal cortex (LIFC) was identified, especially in the alpha and delta bands. In healthy adults, the LIFC is a focal point that features multifrequency interactions with a number of language network regions. The more significant the spectral deviations in the LIFC, the more evident the articulation deficits in patients with PD. The data also revealed that neurophysiological connectivity between LIFC and a network of somatomotor cortices in the beta band independently predicted articulation impairments and fully mediated the effect of cognitive abilities on these impairments.

@zeenam The investigators found that factors such as breastfeeding, mode of birth, and pet exposure, which have been known to affect allergy and asthma, do so by influencing the infant microbiome. In turn, the microbiome affects the development of regulatory T-cells, immunoglobulin E responsiveness, and the development of allergy and asthma symptoms. One of the series was the first human study to show an association between microbial richness, diversity, and evenness in the infant gut and regulatory T-cell development, all of which help keep allergies in check.

Evaluation and treatment of psychiatric emergencies in individuals who are intellectually developmentally disabled pose additional challenges. The goal of crisis intervention is the same as in the general population (ie, to reduce the risk of harm to self/others and to accomplish this objective in the least restrictive setting). For optimum results, the assessment and treatment of patients who are intellectually disabled should include the input of the primary caregivers. Psychiatrists who are unaccustomed to the usual presentation of ID may be nonplussed by the clinical manifestations of psychiatric emergencies in these patients. Limitations in cognition and verbal expression make it difficult for patients to describe abstract concepts such as mood, guilt, and ideas of reference.

Hello, covid cases are rising very high. I am very much worried about this. Does COVID cause stomach upset? What are all the symptoms of covid? Please help me with your information.

@miraj Lips don’t contain oil glands like other parts of the skin. This means lips are more susceptible to drying out and becoming chapped (cracked). Lack of moisture can make the problem worse, whether it’s weather-induced or related to a lack of self-care. Little humidity in the air during the winter months is known to cause chapped lips. Frequent sun exposure in the summer can also worsen your condition. Another common cause of chapped lips is habitual licking. Saliva from the tongue can further strip the lips of moisture, causing more dryness. Chapped lips can usually be treated at home. The first step is to make sure that your lips have enough moisture. This can be accomplished by:
applying lip balm throughout the day
drinking more water
using a humidifier at home
avoiding cold weather conditions or wrapping your mouth with a scarf
Sun exposure can also cause chapped lips, especially as you age. Apply a lip balm that contains a minimum SPF 15 before heading outdoors. The balm helps to moisturize the lips and the sunscreen minimizes further drying effects.

@zeenam Vitamin B12 was discovered as the antipernicious anaemia factor that was found in the liver. The discovery, by two independent teams, of liver as a dietary factor that could reverse anaemia in pernicious anaemia patients led to the Nobel prize in 1934. In the 1930s, researchers started to attempt isolating the ‘active principle’ in liver that contained the antipernicious anaemia factor. In the mean time, the importance of gastric juice for inducing reticulocytosis in pernicious anaemia patients was identified. Only in 1947, two groups independently managed crystallizing the active principle. No other micronutrient than vitamin B12 is known to require a specific factor for its absorption. Without this absorption factor vitamin B12 deficiency follows. Only during the 1950s, this vitamin B12 absorption factor, called intrinsic factor (IF) as opposed to the extrisic factor (vitamin B12 itself) had been to some extent purified.