Interim results from a multidomain interventional study that has the aim of preventing cognitive impairment and disability by managing vascular and lifestyle risk factors show successful reductions in weight, body mass index (BMI), and low-density lipoprotein (LDL) cholesterol levels in patients at risk for dementia, researchers report. Miia Kivipelto, MD, professor of clinical geriatric epidemiology from the Karolinska Institute in Stockholm, Sweden, is leading the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) trial, working with colleagues from the University of Eastern Finland in Kuopio and the University of Helsinki, Finland. She presented these 1-year results of the FINGER study here at the Alzheimer's Disease International (ADI) 27th International Conference.

@gagan There are no effective diagnostic tests or treatments for cognitive PASC, which prompted the investigators to study inflammation in patients with the condition. As reported by Medscape Medical News, the same investigators published initial findings earlier this year. This research showed abnormalities in the CSF in 77% of patients with cognitive impairment. Patients without cognitive impairments had normal CSF. Extending that work in this new study, researchers studied patients from the Long-term Impact of Infection with Novel Coronavirus (LIINC) study with confirmed SARS-CoV-2 infection who were not hospitalized. They conducted 2-hour neurocognitive interviews and identified 23 people with new, persistent cognitive symptoms (cognitive PASC) and 10 with no cognitive symptoms who served as controls.

Recommendations for prescribing exercise to control high blood pressure have been put forward by various medical organizations and expert panels, but finding the bandwidth to craft personalized exercise training for their patients poses a challenge for clinicians. Now, European cardiology societies have issued a consensus statement that offers an algorithm of sorts for developing personalized exercise programs as part of overall management approach for patients with or at risk of high BP.

Phasmophobia, or the fear of ghosts, can be complicated to diagnose. Many people experience a certain thrill of anxiety when telling ghost stories or watching movies that feature ghosts and other supernatural entities. Most are able to control this fear and some even enjoy the feeling that it creates. Some people, however, this fear is overwhelming and life-limiting, thereby meeting the traditional definition of a phobia. Some experts feel that a phobia of ghosts may be symptomatic of a more serious thought disorder, as it may constitute a form of magical thinking. How to convince my toddler to overcome fear of ghost?

@manisha The hba1c is an important reflection of glucose control over a three month period. It gives some guidance as to long-term glucose levels which otherwise change greatly over a day. Glycosylated hemoglobin is due to a covalent bond between glucose and beta chain of haemoglobin. Its percentage is the percentage of glycosylated haemoglobin as of total hemoglobin. The amount is proportional to glucose levels over about 6 weeks. Hba1c of more than 8% requires pharmaco therapeutic management rather than dietary alone. However it is to be kept in mind that hba1c estimates may be less useful in anaemia, pregnancy, uremia and hemoglobinopathies.

Hello, my skin became dry, how many glasses of water should I drink? I learnt that due to lack of water intake I am facing this issue. What should I do apart from drinking plenty of water. Please advise.

Hello, I am 21 years old. I have a problem of constipation. I frequently experience this. My frequency of bowel movement is once in 3-4 days. I have not shared this with any one. What should I do to cure constipation? Please help me with your valuable suggestions.

Hello, my 51-year-old mother in law presented with a new and constant haze with shifting floaters in her right eye (OD) over the past several weeks. Vision and IOP were 20/25 and 22 mm Hg, respectively, OD. She had 1–2+ AC cell with 3–4+ vitreous cell and 1–2+ vitreous haze. There was no retinitis or retinal vasculitis by examination or fluorescein angiography. The left eye was completely uninvolved. She had suffered from episodic ‘black outs’ associated with IOP elevation and recurrent, acute anterior uveitis OD over the preceding 9 years. She was otherwise completely healthy with no significant medical, family or social history. Doctor suggested that it might be the case of intermediate uveitis. Please suggest that how to cure?

Hello, my daughter is twenty eight years old. She is suffering from carpal tunnel syndrome. Her symptoms include tingling, burning, or itching and numbness in the palm of the hand and the fingers, especially the thumb and index finger. Symptoms tend to emerge or get worse after using the affected hand. The sensation of tingling, burning, and pain worsen if the arm or hand has been in the same position for a long time. Please provide some self help tips.

Hi, my father has undergone bypass surgery. He used to drink on a daily basis. He is 56 years old. But the doctor suggested that alcohol consumption within a limit is good for his health. He is also adamant about drinking. I am worried about it. I can not figure out whether alcohol is good for him or not. Please help