Possible triggering factors for exacerbation of asthma
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Hi, in my neighbor's home a 19 year old white woman has come for spending holidays with her mother. She has suffered an asthma attack after collapsing during a winter fun run. Her mother told that she had asthma since the age of 5. She was severely short of breath and unable to speak in full sentences. I would like to understand the pathophysiology of asthma and the possible triggering factors for this exacerbation.
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@Kevin Asthma is a chronic inflammatory disorder of airways, characterized by bronchoconstriction, increased vascular permeability, excess mucus production and impaired muco-ciliary clearance. Due to airway hyper- responsiveness, both specific and non-specific stimuli can trigger the inflammatory response in people with asthma, which is mediated by eosinophils, mast cells, lymphocytes and neutrophils.
Possible triggering factors:
Medicines
Allergens
Running
Non compliance with medication
Infection -