What are the common side effects of paracetamol? Does it affect liver?
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Hello, What are the common side effects of paracetamol? Does it affect liver? Please leave your comments on this. I would like to understand this because paracetamol is a very common drug. It is being used randomly. Please leave your comments on this.
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@kankana The side effects of paracetamol could be low fever with nausea, stomach pain, and lossof appetite; dark urine, clay-colored stools; or. jaundice (yellowing of the skin or eyes). The toxic dose of paracetamol is highly variable. In general the recommended maximum daily dose for healthy adults is 4 grams. Higher doses lead to increasing risk of toxicity. In adults, single doses above 10 grams or 200 mg/kg of bodyweight, whichever is lower, have a reasonable likelihood of causing toxicity. Acetaminophen hepatotoxicity typically presents within 2 to 5 days of an intentional overdose, with a pattern of acute hepatocellular necrosis with striking elevations of aminotransferase levels (often above 2000 U/L and higher than typically seen with acute viral hepatitis) and signs of hepatic failure.