What are the acute and chronic causes of diarrhoea, and what are the investigations required?
Hello, What are the acute and chronic causes of diarrhoea, and what are the investigations required? For last 7 days I am suffering from diarrhoea. Is it normal? Please help me.
@kamal Acute diarrhea is defined as the abrupt onset of 3 or more loose stools per day and lasts no longer than 14 days; chronic or persistent diarrhea is defined as an episode that lasts longer than 14 days. Causes
Infectious - Gastroenteritis, Antibiotic associated colitis, Giardia, amoebiasis (bloody stools)
Inflammatory - Ulcerative colitis (bloody), Crohn's disease
Functional - Irritable bowel syndrome, Laxative abuse
Osmotic - related to oral intake of unabsorbed sugars
Drug induced - laxatives, colchicine, PPIs
Malabsorption - Coeliac disease, Crohn's disease
Neoplastic - colorectal (bloody), rectal villous adenoma (mucus)
Assess stool with Bristol stool scale
Stool microscopy and culture
Clostridium difficile toxin
Check U&E for dehydration. In children consider Haemolytic uraemic syndrome with certain E coli
FBC - elevated WCC, Anaemia - Microcytic suggests possibly a colonic malignancy or inflammatory
bowel disease. Macrocytosis may suggest malabsorption. Dimorphic may suggest both. LFTS - elevated ALP and Bilirubin with obstruction may cause steatorhoea