Pathophysiology of Burning Mouth Syndrome ?
Burning mouth syndrome (BMS) is an idiopathic condition characterized by a continuous burning sensation of the mucosa of the mouth, typically involving the tongue, with or without extension to the lips and oral mucosa. Classically, burning mouth syndrome (BMS) is accompanied by gustatory disturbances (dysgeusia, parageusia) and subjective xerostomia. By definition, no macroscopic alterations in oral mucosa are apparent. Burning mouth syndrome (BMS) occurs most frequently, but not exclusively, in peri-menopausal and postmenopausal women
@prasoon The pathophysiology of burning mouth syndrome (BMS) is not understood. It was originally considered a psychogenic illness; however, a neuropathic mechanism for burning mouth syndrome (BMS) is currently favored. This is based on objectively measured abnormalities of physiologic responses of the trigeminal nerve in burning mouth syndrome (BMS) patients. There is also evidence to suggest histopathologic changes in nociceptive fibers in BMS patients. The differentiation between a peripheral versus a central etiology has not been determined. There is evidence to suggest that anxiety is associated with BMS, but whether it is a cause or the result of intractable symptoms has not been elucidated. However, a literature review by Galli et al indicated that both anxiety and depression may significantly contribute to the development of burning mouth syndrome