Cut Just 300 Calories a Day to Benefit Heart, Even in the Healthy
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Reducing daily food intake by the equivalent of just a couple of cookies, or around 300 calories, over 2 years leads not only to improvements in body composition but a range of cardiometabolic risk factors that could result in reductions in the incidence of cardiovascular disease, the results of an innovative study suggest.
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@shamita The Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE) trial is a phase 2 study involving more than 200 normal to slightly overweight but otherwise healthy individuals up to aged 50 years. They were assigned to a personalized calorie restriction diet combined with individual and group counseling sessions aimed at reducing energy intake by 25%, or an ad libitum control group, who continued with their normal diet.