Sedentary Cancer Survivors Die Sooner Than More-Active Peers
Cancer survivors who spent more than eight hours a day sitting are nearly twice as likely to die over the next handful of years as are those who sit for only four hours, new findings suggest. The analysis of data from more than 1,500 cancer survivors also revealed that being physically active was associated with a much lower risk of cancer-specific death, researchers report in JAMA Oncology.
@dhitishree The exact biologic mechanisms are unclear but the negative effects on metabolic and sex hormones, inflammation, and immunity are some of the main hypothesized pathways. Experimental studies have shown that uninterrupted sitting for long periods is associated with impaired glucose metabolism and increased systematic inflammation, and these can be attenuated by breaking up prolonged sitting.