Fecal Transplant Shows Promise in Reducing Alcohol Craving
Fecal microbiota transplantation results in a short-term reduction in alcohol craving in patients with alcohol-induced cirrhosis who can't stop drinking, results from a new study show. And that reduction could lead to a better psychosocial quality of life for patients with cirrhosis and alcohol use disorder, said investigator Jasmohan Bajaj, MD, from Virginia Commonwealth University in Richmond.
@akhilesh Cirrhosis is associated with an altered gut–brain axis. It leads to organ damage in several parts of the body, including the brain, gut, pancreas, and liver. This makes changing the gut microbes "an attractive target," Bajaj said at the Digital International Liver Congress 2020. For their phase 1 double-blind study, he and his colleagues assessed 20 men from a Virginia veteran's hospital with untreatable alcohol use disorder who were not eligible for liver transplantation.