Memory Complaints Could Signal Dementia Decades Later
Older women who perform normally on a standard cognitive test but who have subjective memory complaints (SMCs) are significantly more likely to have a memory disorder almost two decades later, a new study shows. The strongest association was when SMCs were uncovered just a few years before the cognitive evaluation. Although SMCs have been linked to cognitive impairment in the past, this study was among the first to look at the association over such a long period. The findings suggest that SMCs are an early warning sign of future dementia, said lead author Allison Kaup, PhD, clinical research psychologist, San Francisco Veterans Affairs Medical Center, and assistant professor, Department of Psychiatry, University of California at San Francisco.
@sharbatanu At year 20 of the study (18 years after the baseline SMC assessment), participants were determined by an expert panel to have normal cognition, mild cognitive impairment, or dementia. Women with baseline SMCs were more likely to be diagnosed with cognitive impairment at year 20 compared with women without baseline SMC (52.8% vs 38.0%; P = 0.01).