Amblyopia Treatment More Effective in Younger Children
Treatment of amblyopia is more effective in younger vs older children, according to the results of a meta-analysis of randomized trials reported Online First July 11 in the Archives of Ophthalmology. A research letter in the July issue of the same journal states that an intensive final treatment push with patching and atropine, compared with gradual discontinuation of treatment, did not improve visual acuity in children with mild residual amblyopia.
@taniya Children enrolled in these trials were 3 years old to younger than 13 years, with unilateral amblyopia and 20/40 to 20/400 visual acuity in the amblyopic eye. The main study endpoint was improvement in logMAR amblyopic eye visual acuity, after adjustment for baseline amblyopic eye visual acuity, spherical equivalent refractive error in the amblyopic eye, type of amblyopia, previous treatment of amblyopia, study treatment, and protocol. Because there was a nonlinear association between age and improvement in amblyopic eye visual acuity, 3 age groups were analyzed separately (3 to < 5 years, 5 to < 7 years, and 7 to < 13 years).