REAN Foundation

    • Register
    • Login
    • Search
    • Categories
    • Unread
    • Recent
    • Tags
    • Popular
    • Admin

    Diverse Gut Bacteria in Infants Linked to Reduced Food Allergies

    Child Health
    2
    2
    21
    Loading More Posts
    • Oldest to Newest
    • Newest to Oldest
    • Most Votes
    Reply
    • Reply as topic
    Log in to reply
    This topic has been deleted. Only users with topic management privileges can see it.
    • T
      TIMIR last edited by

      Infants with greater diversity of bacteria in their stools are less likely to have allergies to foods such as egg, milk, or peanuts, researchers say. The finding could lead to new approaches to preventing immunoglobulin E-mediated food allergy (IgE-FA), according to Christine Joseph, PhD, MPH, an epidemiologist in the Henry Ford Health System in Detroit, Michigan, and colleagues.

      S 1 Reply Last reply Reply Quote 0
      • S
        SHYAMALI @TIMIR last edited by

        @timir Food allergies can result when exposure to specific foods activate mast cells and basophils. The allergies may cause atopic eczema in infancy and rhinitis and asthma later in life. In healthy infants, food proteins interact with antigen-presenting cells, but T regulatory cells suppress immune responses, preventing allergies, the researchers write. The relationship between gut bacteria and allergy is complex. Oligosaccharides in human milk that induce the production of interleukin 10 and IgA also stimulate the growth of Bifidobacterium and Lactobacillus, according to the researchers. Clostridia activate the release of TGF-β, which helps induce T regulatory cells to suppress undesirable immune reactions. Gut bacteria also help ferment complex carbohydrates generating short-chain fatty acids, which influence B-cell and intestinal barrier function.

        1 Reply Last reply Reply Quote 0
        • First post
          Last post