Stress Plays Key Role in Developing Long COVID and Cognitive Symptoms
Long COVID is increasingly recognized as a public health burden. Long COVID often results in reduced productivity or an inability to work and places additional strain on other aspects of one's life. Demographic and infection-related characteristics have been identified as risk factors, but less research has focused on psychosocial predictors, such as stress immediately preceding the index infection.
@prachi Odds of self-reported long COVID increased by 1.25 (95% CI: 1.04 – 1.51) for each additional worry about adversity in the month prior to SARS-CoV-2 infection. Individuals in the lowest SEP group were nearly twice as likely to have developed long COVID as those in the highest SEP group (odds ratio [OR]: 1.95; 95% CI: 1.19 – 3.19), and worries about adversity experiences remained a predictor of long COVID (OR: 1.43; 95% CI: 1.04 – 1.98). The number of worries about adversity experiences also corresponded with increased odds of certain long-COVID symptoms, such as difficulty with cognition, by 1.46 (95% CI: 1.02 – 2.09) but not with mobility or self-care.