Treatment and management for mild cognitive impairment

[Rekha]

In mild cognitive impairment (MCI), the changes in cognition exceeds the normal, expected changes related to age. In one classification of MCI, the amnestic form is distinguished from the nonamnestic form. The amnestic form often precedes Alzheimer disease. Symptoms of mild cognitive impairment (MCI) are often vague and include the following:
Memory loss
Language disturbance (eg, difficulty in finding words)
Attention deficit (eg, difficulty in following or focusing on conversations)
Deterioration in visuospatial skills (eg, disorientation in familiar surroundings in the absence of motor and sensory conditions that would account for the complaint)

[Iraban]

@rekha At present, no established treatment exists for mild cognitive impairment (MCI). Cholinesterase inhibitors have not been found to delay the onset of Alzheimer disease (AD) or dementia in individuals with MCI; however, donepezil has been found to delay the progression to AD in MCI patients with depression without affecting their symptoms of depression. There is some evidence to suggest that cognitive interventions may have a positive effect. A practice parameter recommendation by the American Academy of Neurology states that patients with MCI should be identified and monitored because of their increased risk for AD and, to a lesser extent, other dementing conditions. Obviously, correcting (to the extent possible) any sensory and motor manifestations compounding the cognitive symptoms is important for minimizing their impact on MCI.