Depression More Severe, Persistent in the Elderly
Older adults with major depressive disorder (MDD) have a substantially worse prognoses than their younger counterparts, new research suggests. A 2-year observational study showed that the course of MDD worsened linearly with age, such that individuals aged 70 years and older had the worst outcomes. These findings persisted after the researchers adjusted for clinical, social, and health factors.
@anirban It is expected that almost one fifth of adults will have at least one episode of MDD at some point during their lives, but the course of such episodes "can be highly variable," the authors write. Previous studies, said Schaakxs, show that the course of MDD is more unfavorable in older age. However, she noted that studies with "solid methodology" that carefully take into account other prognostic factors are lacking.