Worsening Motor Function Tied to Post-COVID Syndrome in Parkinson's
Decreased motor function, as well as other adverse outcomes, are linked to post-COVID-19 syndrome in patients with Parkinson's disease (PD), new research suggests. Results from a small, international retrospective case study show that about half of participants with PD who developed post-COVID-19 syndrome experienced a worsening of motor symptoms and that their need for anti-Parkinson's medication increased.
@manju Previous studies have documented worsening of motor and nonmotor symptoms among PD patients in the acute phase of COVID-19. Results of these study suggest that mortality may be higher among patients with more advanced PD, comorbidities, and frailty. Leta noted that long-term sequelae with so-called long COVID have not been adequately explored, prompting the current study. The case series included 27 patients with PD in the United Kingdom, Italy, Romania, and Mexico who were also affected by COVID-19. The investigators defined post-COVID-19 syndrome as "signs and symptoms that develop during or after an infection consistent with COVID-19, continue for more than 12 weeks, and are not explained by an alternative diagnosis