Calcium Supplements Linked to Worse Outcome in Aortic Stenosis
Oral calcium supplementation was associated with lower survival and a greater need for aortic valve replacement in elderly patients with mild to moderate aortic stenosis, a new study finds. The researchers, led by Nicholas Kassis, MD, Cleveland Clinic Foundation, Cleveland, Ohio, explain that aortic stenosis is the most common adult valvular disease in the developed world. Increasing with age, it has a prevalence of 2% among those over 65 years and 4% over 85 years. The condition is marked by severe calcification causing leaflet immobility and outflow obstruction, a process that occurs over a mean duration of 8 years and leads to dramatically increased mortality if left untreated once symptoms develop. With no proven pharmacological therapy, aortic valve replacement is the only treatment modality.
@sanghbarta The current study included 2657 patients (mean age, 74 years; 42% women) with mild to moderate native aortic stenosis selected from the Cleveland Clinic Echocardiography Database from 2008 to 2016 and followed for a median duration of 69 months.