'First Evidence' Links Gut Bacteria, Fibromyalgia
Patients with fibromyalgia appear to have specific gut microbiome alterations that differ from their healthy peers, new research suggests. In the "first evidence" to show this connection, investigators found that women with fibromyalgia had significant differences in 19 species of gut bacteria compared with healthy controls. They also had higher serum levels of butyrate and lower levels of propionate. In addition, machine-learning algorithms showed diagnostic prediction accuracy ratings of 87%–88%.
@plaban The pathophysiology of fibromyalgia is not well understood, the investigators note. There are multiple hypotheses being suggested, including impaired central nervous system nociceptive processing, altered peripheral nociception, and systemic inflammation