Probiotics Promising for Mild to Moderate Depression
Probiotics may be effective in reducing core depressive symptoms in treatment-naive patients with a mild to moderate form of the disorder, results of a new pilot study suggest. Investigators led by Caroline Wallace, PhD candidate, Queen's University, Kingston, Ontario, Canada, found that symptoms of mood, anhedonia, and sleep disturbance were significantly reduced with probiotic therapy after just 4 weeks, with results maintained at 8 weeks. The findings are of particular interest because probiotics are not associated with any of the adverse effects of current antidepressant therapies and can be safely taken over long periods.
@ori Molecular markers of inflammation were assessed and tryptophan and serotonin levels were determined. The patients underwent polysomnographic assessment to measure objective sleep.