Antihypertensives'' Ability to Cross Blood–Brain Barrier Tied to Cognitive Changes
Older hypertensive patients taking renin-angiotensin drugs that cross the blood-brain barrier (BBB) show slightly less memory decline over time than do those taking non-penetrant antihypertensives, a new meta-analysis suggests. Conversely, they had worse attention over time, researchers report in the journal Hypertension.
@plaban Several factors may explain this unexpected finding. In contrast to memory recall ability, attentional processes may be impacted by spurious factors unrelated to neuropathological processes, including test engagement, stress, and depression.