Constipation Med Boosts Cognitive Performance in Mental Illness
A drug approved to treat constipation appears to improve cognitive impairment and boost brain activity for patients with mental illness, new research suggests. In a randomized controlled trial, 44 healthy individuals were assigned to receive the selective serotonin-4 (5-HT4) receptor agonist prucalopride (Motegrity) or placebo for 1 week. After 6 days, the active-treatment group performed significantly better on memory tests than the participants who received placebo. In addition, the drug increased activity in brain areas related to cognition.
@putin Even when the low mood associated with depression is well-treated with conventional antidepressants, many patients continue to experience problems with their memory.