Curcumin for osteoarthritis management!!
Hello, I am Vatan, studying in eleventh standard. My mother is an osteoarthritis patient. I have seen her suffering a lot. My father is staying away from us, so it is very difficult for my mother to take care of our family in her ailing state. She has tried all sorts of anti-inflammatory drugs to reduce her pain. No drug is able to provide permanent solution. I am worried for her. I came to know from my teacher that curcumin is effective in treating osteoarthritis. It is a natural product, so it has got minimal or no adverse effect. Can anybody please explain the role of curcumin in osteoarthritis management.
@vatan The management of osteoarthritis (OA) represents a real challenge. This complex and multi-factorial disease evolves over decades and requires not only the alleviation of symptoms, i.e. pain and joint function but also the preservation of articular structure without side effects. Nutraceuticals are good candidates for the management of OA due to their safety profile and potential efficacy. However, they are not part of the treatment guidelines and published recommendations. Curcumin is the yellow pigment isolated from the rhizomes of Curcuma longa, commonly known as turmeric. Curcumin is a highly pleiotropic molecule with an excellent safety profile. Strong molecular evidence has been published for its potency to target multiple inflammatory diseases. However, naturally occurring curcumin cannot achieve its optimum therapeutic outcomes due to its low solubility and poor bioavailability. Nevertheless, curcumin presents great potential for treating OA and has been categorized as having preclinical evidence of efficacy.