'DIY' Artificial Pancreas Systems Found to Be Safe, Effective
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Open-source automated insulin delivery systems appear to be both effective and safe in adults and children, new research finds. Automated insulin delivery (AID) system, also known as closed-loop systems or an artificial pancreas, link an insulin pump and a continuous glucose monitor (CGM) with an algorithm that automatically adjusts insulin delivery to optimize glycemic control. Prior to the availability of commercial AID systems, Dana Lewis, a patient with type 1 diabetes, and her partner co-developed an algorithm that could link older versions of an insulin pump and CGM.
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@paromita AID systems are not approved by any regulatory body, and despite several nonrandomized studies demonstrating their effectiveness and safety, there is still concern among some health professionals about their safety. In 2019, the US Food and Drug Administration (FDA) warned against the use of any nonapproved devices or algorithms. (Now, though, at least one open-source AID system algorithm is under FDA review.) Aimed at addressing those concerns, CREATE (Community Derived Automated Insulin Delivery) is the first randomized controlled clinical trial to compare an open-source AID system to insulin pump therapy and CGM (without any communication between the two) in patients with type 1 diabetes, most of whom were naive to AID systems.