Biomarker in the Eye May Flag Neurodegeneration Risk

[Atharva]

Neurofilament light chain (NfL), a biomarker previously measured in blood or cerebrospinal fluid and used to indicate neurodegeneration, is detectable in the vitreous humor of the eye, opening the door to a potential new method of predicting neurodegenerative disease, new research suggests.

[Anaika]

@atharva Recent research has identified NfL as a potential screening tool and some researchers believe it to be on the verge of clinical applicability. In addition, increased levels of the biomarker have been observed in both the cerebrospinal fluid (CSF) and blood of individuals with neurodegeneration and neurological diseases, including AD. In previous studies, for example, elevated levels of NfL in CSF and blood have been shown to reliably distinguish between patients with AD and healthy volunteers