Prognosis of Tuberculosis
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What is the prognosis of tuberculosis ?
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@quincy Full resolution is generally expected with few complications in cases of non-MDR- and non-XDR-TB, when the drug regimen is completed. Among published studies involving DOT treatment of TB, the rate of recurrence ranges from 0-14%. In countries with low TB rates, recurrences usually occur within 12 months of treatment completion and are due to relapse. In countries with higher TB rates, most recurrences after appropriate treatment are probably due to reinfection rather than relapse.
Poor prognostic markers include extrapulmonary involvement, an immunocompromised state, older age, and a history of previous treatment. In a prospective study of 199 patients with TB in Malawi, 12 (6%) died. Risk factors for dying were reduced baseline TNF-α response to stimulation (with heat-killed M tuberculosis), low body mass index, and elevated respiratory rate at TB diagnosis.