Can Exercise Prevent Cognitive Decline in Early Parkinson's?
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Exercise might help prevent cognitive decline in high-risk patients with early Parkinson's disease (PD), new research suggests. Investigators found PD patients who were APOE ε4 carriers had greater cognitive decline compared to non-APOE ε4 carriers, but the findings also revealed higher physical activity appeared to slow cognitive decline in this higher risk group.
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@premomay Previous research shows physical activity has beneficial effects in PD, but the mechanism underlying these effects are not well understood. Additional data suggest physical activity modifies the APOE ε4 effect on the development and progression of AD.