Intermittent claudication in peripheral vascular disease (PVD)?

[Uana]

How is intermittent claudication characterized in peripheral vascular disease (PVD)?

[Olivia]

@uana Intermittent claudication may be the sole manifestation of early symptomatic PVD. The level of arterial compromise and the location of the claudication are closely related, as follows:

Aortoiliac disease manifests as pain in the thigh and buttock, whereas femoropopliteal disease manifests as pain in the calf
Symptoms are precipitated by walking a predictable distance and are relieved by rest
Collateral circulation may develop, reducing the symptoms of intermittent claudication, but failure to control precipitant factors and risk factors often causes its reemergence
Claudication may also present as the hip or leg "giving out" after a certain period of exertion and may not demonstrate the typical symptom of pain on exertion
The pain of claudication usually does not occur with sitting or standing