Obesity Gene Variants Predict Overeating in Slim Children
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Children who were not obese and were allowed to eat as much as they wanted of a lunch of familiar foods ate more if they had certain fat mass- and obesity-associated (FTO) gene variants. Specifically, children with the AT obesity gene variant consumed 64 more calories than children with the TT variant, and children with the AA variant consumed 128 more calories than children with the TT variant — after adjusting for body weight and calories eaten in the previous meal.
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@prachi Results corroborate and extend prior work [in children and adults with obesity] by showing a dose-dependent effect [of A alleles of the FTO gene] on food intake in children without obesity