New Insight on How a Western Diet May Cause Colorectal Cancer
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New research points to a strong association between a Western-style diet and a subgroup of colorectal cancer (CRC) containing abundant polyketide synthase (pks+) Escherichia coli, supporting a potential link between diet, the intestinal microbiota, and colorectal carcinogenesis, the researchers say. Colibactin-producing pks+ E coli was recently found to cause DNA mutations in colonic cells, study investigator Shuji Ogino, MD, PhD, Department of Pathology, Brigham and Women's Hospital, Boston, told Medscape Medical News.
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@sandipan Considering the possible interplay between diet and pathogenic bacteria, it is of particular interest to study Western-style diet in relation to pks+ E coli within colorectal tumor tissue