What is the role of anxiety in the pathophysiology of burning mouth syndrome (BMS)?
There is evidence to suggest that anxiety is associated with BMS, but whether it is a cause or the result of intractable symptoms has not been elucidated. However, a literature review by Galli et al indicated that both anxiety and depression may significantly contribute to the development of burning mouth syndrome
@awanish The pathophysiology of burning mouth syndrome (BMS) is not understood. It was originally considered a psychogenic illness; however, a neuropathic mechanism for burning mouth syndrome (BMS) is currently favored. This is based on objectively measured abnormalities of physiologic responses of the trigeminal nerve in burning mouth syndrome (BMS) patients. There is also evidence to suggest histopathologic changes in nociceptive fibers in BMS patients. The differentiation between a peripheral versus a central etiology has not been determined.