Is it essential to take antacids with NSAIDs?
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Hello, I am 32 years old. I have got severe toothache. I have no other medical history of illness. I went to the dentist and she prescribed me NSAIDs and antacids. I was advised to take both. I have an aversion for medicines. Because they have adverse effects. What is the need of taking antacids, as I do not have gastric problems. Shall I change the dentist? Is it essential to take antacids with NSAIDs?
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@paromita NSAIDs are a leading cause of drug-related morbidity, especially in the elderly and patients with comorbidities. Adverse events associated with NSAIDs are a challenge in treatment optimization for pain. Adverse events include alterations in renal function, effects on blood pressure, hepatic injury, and platelet inhibition, which may result in increased bleeding. However, the most important adverse effect of NSAIDs is the gastrointestinal (GI) adverse effects. Proton-pump inhibitors (PPIs) have been proven efficacious in healing NSAID-associated ulcers, as they provide potent and long-lasting inhibition of gastric acid secretion.