Two Distinct Subtypes of PCOS Identified in Adolescents
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Polycystic ovary syndrome (PCOS) in adolescents appears to present as two distinct subtypes based on the presence or absence of obesity, new data show. The findings support the "metabolic" and "reproductive" subtypes previously identified in adult women, say the researchers. Overall, PCOS affects 7% to 10% of adult women and is associated with significant metabolic and reproductive comorbidities, including type 2 diabetes, metabolic syndrome, subfertility, and endometrial carcinoma.
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@sohini Diagnostic criteria vary, but in general the diagnosis is made by the presence of combinations of hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology. In adolescents, only the first two are criteria used for diagnosis of PCOS, and the definition of oligo- and/or anovulation differs from that of adult women.